Microwaving each disc for a couple of seconds will be sufficient to destroy it - see https://www.youtube.com/watch?v=lKd92oU9ivs from about 10 seconds in - this is a slow-mo video, the actual effect happens in less than a second
Find a solvent that attacks the plastic - acetone or gasoline would be the ones I try first
Use a solvent that attacks the aluminium mirroring - (car) battery acid is relatively common from specialist suppliers, and is occasionally marketed as drain cleaner
Use a sander to remove a large percentage of the label side
Set them on fire
Bolt 20 together at a time and drill large holes in them. CDs are read from centre to edge, so destroying the centremost circumference will make the rest of the disc unreadable to all except specialist equipment
Hold the CD between thumb and fingers so the label is facing your palm. Use emery (sanding) paper to scratch the non-label side (just need a few small cuts in the surface- a single wipe across the diameter should do) along the line that the CD will fold when you bend it. Try and fold it in half - it'll shatter into pieces. If you're finding they do fold and you want them shattered, freeze them first and fold them while still cold
Lay them out in a line and run a blowtorch over the label side, blistering it. Only need to do a single line across the diameter to make them predominantly unusable